H29年度 特別課題演習実施内容

Biochemical Engineering Lab. (Omasa, Koga)

In this laboratory, we deal with the design, operation and optimization of bioprocesses concerned with the production of biological product by microbial and mammalian cells, including up- and down-stream processing working with industries. In this research exercise, students will be promoted to learn the research works currently performed in this laboratory and to understand the recent progress in this field.

  • Orientation of research projects in the lab and lab-trip.
  • Basic training of mammalian cell culture and protein engineering.
  • Reading and discussion about recent research topics.



  • 領域の研究概要の説明と見学
  • 動物細胞実験またはタンパク質工学基礎実験
  • 最新トピックスについての文献講読、質疑応答

Organic Electronic Materials Science Lab. (Nakayama, Suenobu)

We have been studying optoelectronic functions of organic materials. We intend to develop new concept devices via understanding fundamental properties of organic materials. In this research exercise, students will experience fabrication and measurements on organic devices.

  • Orientation of research projects and lab tour.
  • Fabrication and measurements of organic devices.
  • Discussion and report.



  • 研究概要の説明と、研究室の見学
  • 有機デバイスの作製と測定
  • 質疑応答とレポート

Chemistry on Supramolecular Recognition Lab. (Tohnai, Hisaki)

 One of the research aims in Miyata lab. is to chemically reveal how molecules recognized one another in supramolecular assemblies (chemistry on supramolecular recognition). In this exercise, first you can learn the past, present, and feature of the chemistry. Subsequently, you can perform exercises including fundamental experiments required for understanding supramolecular recognition, listed as follows:

  • Lab. tour and handling molecules with models and computational graphic tools.
  • Simple organic syntheses, crystallization of the products, various analyses of the resulting crystalline powders, and crystallographic analyses of single crystals.
  • Thinking about how molecules recognize each other and demonstration of the mechanism for supramolecular recognition.
  • Discussion and report



  • 領域の研究概要の説明と研究室見学、分子模型と分子グラフィックス
  • 簡単な有機合成、再結晶と蒸留、包接結晶の機器分析、単結晶のX線構造解析
  • 分子認識の実例と仕組み
  • 質疑応答とレポート

Chemical Biology Lab. (Kikuchi, Hori, Minoshima)

 The major focus of research in our laboratory is the design, synthesis and application of chemical tools for clarification of various biological phenomena. The purpose of the “Project-based training course” in our laboratory is to master the basic skills of protein expression and purification, and to learn a protein labeling technology. Furthermore, the recent researches on chemical biology are discussed on the final day. The research plan is as follows:

  • Introduction and laboratory tour
  • Expression and purification of recombinant proteins
  • Protein labeling with synthetic fluorescent probes
  • Discussion and report


 本領域では“生命現象を明らかにするための化学ツール (Chemical Tool)のデザイン・合成・生物応用”を主要テーマとしています。本年度の特別課題演習では大腸菌における蛋白質の発現・精製の基礎と合成蛍光プローブによる蛋白質の蛍光標識実験について習得する。さらに、ケミカルバイオロジー分野における最近の研究について検討する。

  • 領域の研究概要の説明と研究室見学
  • 組換えタンパク質の発現・精製
  • 合成蛍光プローブによる蛋白質の蛍光標識実験
  • 質疑応答とレポート

Biofunctional Chemistry Lab. (Itoh, Sugimoto, Morimoto)

 The general goal of our research is to understand enzymatic catalysis at a molecular level and to apply them as artificial bio–inspired catalysts and devices. In this project, we will provide a subject of modeling studies of metalloprotein active sites. In addition, overview of this research area and perspective are introduced.

  • Introduction and laboratory tour
  • Synthetic experiments and characterization of model compounds including crystal structural determination
  • Evaluation of the model compounds in catalytic reactions.
  • Discussion and report



  • 領域の研究概要の説明と研究室見学、テーマ設定
  • 合成実験、物性評価、結晶構造解析
  • 触媒反応性の評価
  • 質疑応答とレポート

Advanced Engineering Physics Lab. (Takai, Kimura)

 In our Lab., we have been involved in researches of the development of noble apparatuses and techniques to investigate the structure, composition, and electronic state of various kinds of materials, such as bio-, inorganic, and organic materials, at atomic scale by using electrons, X-ray photons, and ions. We also apply those apparatus and techniques to elucidate various phenomena occurring at the surface and interface of materials. In Research Exercises in Special Topics of this year, we are going to provide following exercises in order to help you to understand the interaction of electrons with solids, which is the basic physics required for the materials analysis using electrons.

  • Introduction to our research programs and Lab. tour.
  • Preparation of Au poly-crystalline specimen for the observation by transmission electron microscope (TEM), TEM observation of Au specimen, the analysis of experimental results, and the submission of the report. (The deadline of the submission of the report is 2 week after finishing the exercise.



  • 領域の研究概要の説明と見学.
  • 透過型電子顕微鏡用多結晶試料(Au)の作製と透過型電子顕微鏡による観察,実験結果の解析を行い,レポートにまとめて提出する. (レポート提出期限,2週間後)

Photonic Information Technology Lab (Konishi)

 Our laboratory is engaged in research and education in interdisciplinary fields related to optics, image processing, and signal processing. Light is multi-dimensional phenomena in time and space, and such properties can be utilized for realizing a variety of functions. To understand this point as well as basics of information processing using light, we are going to conduct experiments based on light-matter interaction.

  • Refraction, reflection, diffraction of light
  • Measurement of refractive index and absorbance
  • Construction of optical switch
  • Seminar presentation
  • Report



  • 光パルスの理解
  • 光パルスによる非線形な光物性計測の基礎実験
  • 非線形な光物性を用いた光信号処理の基礎実験
  • 発表会
  • レポート提出

Applied Surface Science Lab. (Watanabe, Shimura, Hosoi)

 In order to realize an "ubiquitous network society" that all users can access whenever they wish from wherever they wish, much faster operation and lower power consumption are required for future electronic devices. Our laboratory aims to develop and evaluate advanced electronic materials and novel device fabrication processes as part of this movement. In this program, participating students experience a class 1 clean room and handling our laboratory equipments with several semiconductor materials (Si, Ge, SiC).

  • Introduction of our research and laboratory tour
  • Fabrication of semiconductor devices
  • Electrical and physical characterization



  • 研究概要の説明と実験施設/装置の見学
  • 半導体デバイス作製実験
  • デバイス特性評価・物性解析


本領域では、先端レーザー技術を用い、光と物質の相互作用を通じて物質系の非平衡ダイナミクスを明らかにすること、また、ダイナミクスに関する知 見を基礎とした新しい分光技術の開発を行っています。また、そのための計測手法の開発を行っています。 今年度の特別課題演習では、非平衡現象の観察とその計測を行ないます。自然界では自発的にリズムをきざむ現象が一般的にみられます。たとえば、心 臓の鼓動 や、呼吸、概日リズム、月経サイクルなどはなじみがあるでしょう。このような振動現象は自励振動と呼ばれています。今回、自励振動のモデルとして よく知ら れている塩水振動子を実際に構築し観察を行ないます。また、レーザーやハイスピードカメラ等を用いて、振動の様子を計測し定量的な解析も行います。この実 験を通して非平衡現象への理解と関心を深めていくことを目指します。

  • 実施内容
    • 塩水振動子について
    • 塩水振動子の作成
    • 塩水振動子の観察と計測