what is supramolecular chemistry)

Our Miyata lab’s  study is very different from yours. So firstly I want to talk about supramolecular chemistry,our theme briefly.

It is said Molecular chemistry is study of controling covalent bond

.

and Supramolecular chemistry is study of controling noncovalent bond.

And bio also maintain it’s functon by control noncovalent bond especially hydrogenbond.

Biology has complexity but don’t have variety and expanse

on the other hand chemistry doesn’t have complexity copared with biology.

Lehn said Supramolecular chemistry play a role in filling this blank.

Intro)

Next I want to talk about centraldogma.

When protein is synthesized in vivo, t-RNA is stacking to the m-RNA by hydrogen bond. And the information of m-RNA is copied to Protein. This transmission happened only in bio, and It’S difficult in chemistry.

But this function is very useful in future, so we makes model of transmisson.

We use alkylchain for the this linear molecules, and set out some secondary ammonium salts on this alkylchain. We use secondary ammonium cation , because secondary ammonium can be set out on alkylchain . and we know much about ammonium by our study. 　And next, we should design the receptor which is stacking with secondary ammonium salts by hydrogenbond.

Design)

Next, please talk about molecular design.

Small insect makes small nest, and big bird makes big nest . cause their body fits the nest size. And we reveal Pybox ligands is best for the secondary ammonium.

Because Pybox has lone pair suitable for hydrogenbonding with secondary ammonium salts. So we use Pybox as receptor .for secondary ammonium salts.

This presentation)

I want to talk about this two points.

Firstly, I changed the number of carbon atoms between secondary ammoniums.

And secondary, I change the counter anion of secondary ammonium cations.

How Pybox stacking)

I synsesize these compound. You know the number of carbon atoms be changed form two to six. One can be changed,so omitted.